Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
Mol Cell Biol
1986 Jan 01;61:218-26. doi: 10.1128/mcb.6.1.218-226.1986.
Show Gene links
Show Anatomy links
Sequences from sea urchin TU transposons are conserved among multiple eucaryotic species, including humans.
Liebermann D
,
Hoffman-Liebermann B
,
Troutt AB
,
Kedes L
,
Cohen SN
.
???displayArticle.abstract???
Sequences homologous to various structural domains of the Strongylocentrotus purpuratus TU family of transposons are present in sea urchin species closely related to S. purpuratus and were found in close proximity to each other in linkage patterns that differed for different species. Sequence homologs of the inverted repeat outer domain (IVR-OD) segment were, in addition, present in a sea urchin related only distantly to S. purpuratus and in all other eucaryotic organisms surveyed. In humans, a polymorphic hybridization pattern was seen for genomic DNA obtained from different individuals. Sequence comparisons revealed that repeated sequence motifs similar to those making up the 15-base-pair direct repeat unit of the IVR-OD domain of the TU elements exist in the IVRs of transposons identified in Drosophila melanogaster and maize and in the transcription control regions of certain eucaryotic viral and cellular genes. The remarkable evolutionary conservation of IVR-OD homologs may reflect a biological role for these sequences in DNA transposition, the regulation of gene expression, or both.
Anderson,
Repetitive sequences of the sea urchin genome. Distribution of members of specific repetitive families.
1981, Pubmed,
Echinobase
Anderson,
Repetitive sequences of the sea urchin genome. Distribution of members of specific repetitive families.
1981,
Pubmed
,
Echinobase
Baltimore,
Retroviruses and retrotransposons: the role of reverse transcription in shaping the eukaryotic genome.
1985,
Pubmed
Barker,
Nucleotide sequence of the maize transposable element Mul.
1984,
Pubmed
Benoist,
In vivo sequence requirements of the SV40 early promotor region.
1981,
Pubmed
Benton,
Screening lambdagt recombinant clones by hybridization to single plaques in situ.
1977,
Pubmed
Cairns,
The origin of human cancers.
1981,
Pubmed
Conrad,
Isolation and characterization of human DNA fragments with nucleotide sequence homologies with the simian virus 40 regulatory region.
1982,
Pubmed
Davidson,
Repetitive sequence transcripts in development.
1982,
Pubmed
,
Echinobase
Dierks,
Three regions upstream from the cap site are required for efficient and accurate transcription of the rabbit beta-globin gene in mouse 3T6 cells.
1983,
Pubmed
Dover,
Molecular drive: a cohesive mode of species evolution.
1982,
Pubmed
Dynan,
Transcription factor Sp1 recognizes promoter sequences from the monkey genome that are simian virus 40 promoter.
1985,
Pubmed
Döring,
DNA sequence of the maize transposable element Dissociation.
1984,
Pubmed
Döring,
Barbara McClintock's controlling elements: now at the DNA level.
1985,
Pubmed
Erwin,
"Hopeful monsters," transposons, and Metazoan radiation.
2010,
Pubmed
Everett,
The repeated GC-rich motifs upstream from the TATA box are important elements of the SV40 early promoter.
1983,
Pubmed
Finnegan,
Transposable elements in eukaryotes.
1985,
Pubmed
Fromm,
Deletion mapping of DNA regions required for SV40 early region promoter function in vivo.
1983,
Pubmed
Hartzell,
SV40 deletion mutants lacking the 21-bp repeated sequences are viable, but have noncomplementable deficiencies.
1983,
Pubmed
Hartzell,
Mapping of the late promoter of simian virus 40.
1984,
Pubmed
Hoffman-Liebermann,
TU elements: a heterogeneous family of modularly structured eucaryotic transposons.
1985,
Pubmed
,
Echinobase
Johnson,
Insertion of a short repetitive sequence (D88I) in a sea urchin gene: a typical interspersed repeat?
1985,
Pubmed
,
Echinobase
Kedes,
The organization of sea urchin histone genes.
1978,
Pubmed
,
Echinobase
Khoury,
Enhancer elements.
1983,
Pubmed
Kleckner,
Transposable elements in prokaryotes.
1982,
Pubmed
Klein,
The role of gene dosage and genetic transpositions in carcinogenesis.
1982,
Pubmed
Levis,
FB elements are the common basis for the instability of the wDZL and wC Drosophila mutations.
1983,
Pubmed
Liebermann,
An unusual transposon with long terminal inverted repeats in the sea urchin Strongylocentrotus purpuratus.
1984,
Pubmed
,
Echinobase
MCCLINTOCK,
Controlling elements and the gene.
2002,
Pubmed
McCutchan,
DNA sequences similar to those around the simian virus 40 origin of replication are present in the monkey genome.
1981,
Pubmed
McKnight,
Transcriptional control signals of a eukaryotic protein-coding gene.
1982,
Pubmed
McKnight,
The distal transcription signals of the herpesvirus tk gene share a common hexanucleotide control sequence.
1984,
Pubmed
Mishoe,
Simian virus 40 guanine-cytosine-rich sequences function as independent transcriptional control elements in vitro.
1985,
Pubmed
Potter,
Eucaryotic transposable genetic elements with inverted terminal repeats.
1980,
Pubmed
Potter,
DNA sequence of a foldback transposable element in Drosophila.
1982,
Pubmed
Queen,
Three segments from the monkey genome that hybridize to simian virus 40 have common structural elements.
1982,
Pubmed
Rigby,
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.
1977,
Pubmed
Roberts,
Comparison of sea urchin and human mtDNA: evolutionary rearrangement.
1983,
Pubmed
,
Echinobase
Rosenthal,
BK viral enhancer element and a human cellular homolog.
1983,
Pubmed
Rosenzweig,
Sequence of the C. elegans transposable element Tc1.
1983,
Pubmed
Saffer,
Transcription from SV 40-like monkey DNA sequences.
1984,
Pubmed
Scheller,
Repetitive sequences of the sea urchin genome. II. Subfamily structure and evolutionary conservation.
1982,
Pubmed
,
Echinobase
Seif,
The genome of human papovavirus BKV.
1980,
Pubmed
Southern,
Detection of specific sequences among DNA fragments separated by gel electrophoresis.
1976,
Pubmed
Syvanen,
The evolutionary implications of mobile genetic elements.
1985,
Pubmed
Truett,
Unusual structure of the FB family of transposable elements in Drosophila.
1981,
Pubmed
Weiher,
Multiple point mutations affecting the simian virus 40 enhancer.
1983,
Pubmed
Zuker,
Dictyostelium transposable element DIRS-1 has 350-base-pair inverted terminal repeats that contain a heat shock promoter.
1984,
Pubmed
