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Echinobase
ECB-ART-31117
Immunol Today 1992 Sep 01;139:356-62. doi: 10.1016/0167-5699(92)90172-4.
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The echinoid immune system and the phylogenetic occurrence of immune mechanisms in deuterostomes.



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In this article, Courtney Smith and Eric Davidson reinterpret the published data on immune function in lower deuterostomes and primitive chordates. It leads them to a new model of immune system phylogeny in which MHC-directed T-cell responses are the last to evolve and are not derived from subchordate self-nonself recognition systems.

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Genes referenced: LOC115919910