ECB-ART-42859
Carbohydr Polym
2013 Jun 05;951:9-15. doi: 10.1016/j.carbpol.2013.02.035.
Show Gene links
Show Anatomy links
The antioxidant activities and neuroprotective effect of polysaccharides from the starfish Asterias rollestoni.
???displayArticle.abstract???
After the starfish was defatted with isopropyl alcohol and ethanol, crude polysaccharide was extracted by 0.15 mol/L HCl. Anion exchange chromatography was performed to fractionate the sample into two fractions, SF-1 and SF-2. Chemical analysis showed that the major component of SF-1 was a glucan consisting of a backbone of 1→3 linked β-D-glucopyranose residues, and it had a minor glucan component containing a backbone of 1→3 linked α-D-glucopyranose residues. SF-2 was a mannoglucan sulfate. SF-2 displayed the highest antioxidant activity among the polysaccharides. Moreover, SF-1 and SF-2 exhibited neuroprotective activities in a neurotoxicity model of Parkinson''s disease (PD).
???displayArticle.pubmedLink??? 23618233
???displayArticle.link??? Carbohydr Polym