Click
here to close Hello! We notice that
you are using Internet Explorer, which is not supported by Echinobase
and may cause the site to display incorrectly. We suggest using a
current version of Chrome,
FireFox,
or Safari.
Proc Natl Acad Sci U S A
1981 May 01;785:2856-60. doi: 10.1073/pnas.78.5.2856.
Show Gene links
Show Anatomy links
Histone genes are clustered but not tandemly repeated in the chicken genome.
Engel JD
,
Dodgson JB
.
???displayArticle.abstract???
The recombinant chicken DNA library was screened for histone genes by using pSp17, a recombinant sea urchin DNA probe containing the H2a and H3 genes of Strongylocentrotus purpuratus. Three of the isolated lambda recombinants have been analyzed by restriction enzyme mapping and Southern blotting; one histone H3 gene-encoding recombinant was further analyzed by DNA sequence determination. These studies reveal that the chicken histone genes are not tandemly reiterated, but that, at the least, several histone genes are physically closely linked in a nonrepetitive arrangement within the chicken genome. The evolutionary implications of this arrangement versus that seen in Drosophila and sea urchins is discussed.
Arceci,
The programmed switch in lysine-rich histone synthesis at gastrulation.
1976, Pubmed,
Echinobase
Arceci,
The programmed switch in lysine-rich histone synthesis at gastrulation.
1976,
Pubmed
,
Echinobase
Crawford,
Histone genes are clustered with a 15-kilobase repeat in the chicken genome.
1979,
Pubmed
Dugaiczyk,
Ligation of EcoRI endonuclease-generated DNA fragments into linear and circular structures.
1975,
Pubmed
Engel,
Analysis of the closely linked adult chicken alpha-globin genes in recombinant DNAs.
1980,
Pubmed
Girvitz,
A rapid and efficient procedure for the purification of DNA from agarose gels.
1981,
Pubmed
Herrmann,
Conversion of bacteriophage fd into an efficient single-stranded DNA vector system.
1980,
Pubmed
Jacob,
Histone-gene reiteration in the genome of mouse.
1976,
Pubmed
,
Echinobase
Kedes,
Reiteration and clustering of DNA sequences complementary to histone messenger RNA.
1971,
Pubmed
Kedes,
The organization of sea urchin histone genes.
1978,
Pubmed
,
Echinobase
Klein,
A rapid microscale technique for isolation of recombinant plasmid DNA suitable for restriction enzyme analysis.
1982,
Pubmed
Lacy,
The linkage arrangement of four rabbit beta-like globin genes.
1980,
Pubmed
Lifton,
The organization of the histone genes in Drosophila melanogaster: functional and evolutionary implications.
1978,
Pubmed
,
Echinobase
Long,
Repeated genes in eukaryotes.
1980,
Pubmed
Maniatis,
Nucleotide sequence of the rightward operator of phage lambda.
1975,
Pubmed
Maniatis,
Chain length determination of small double- and single-stranded DNA molecules by polyacrylamide gel electrophoresis.
1975,
Pubmed
Maxam,
Sequencing end-labeled DNA with base-specific chemical cleavages.
1980,
Pubmed
Scott,
Reiteration frequency of the gene for tissue-specific histone H5 in the chicken genome.
1976,
Pubmed
Smith,
A simple method for DNA restriction site mapping.
1976,
Pubmed
,
Echinobase
Sures,
The DNA sequence of sea urchin (S. purpuratus) H2A, H2B and H3 histone coding and spacer regions.
1979,
Pubmed
,
Echinobase
Tabak,
A method for the recovery of DNA from agarose gels.
1978,
Pubmed
Weinberg,
Histone gene arrangement in the sea urchin, Strongylocentrotus purpuratus.
1976,
Pubmed
,
Echinobase
Wilson,
Reiteration frequency of histone coding sequences in man.
1975,
Pubmed