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Echinobase
ECB-ART-48166
Chem Pharm Bull (Tokyo) 2007 Mar 01;553:462-3. doi: 10.1248/cpb.55.462.
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Neuritogenic activity of gangliosides from echinoderms and their structure-activity relationship.

Kaneko M , Yamada K , Miyamoto T , Inagaki M , Higuchi R .


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The effects of the gangliosides isolated from echinoderms on the neuritogenesis of a rat pheochromocytoma cell line (PC-12 cells) in the presence of nerve growth factor were investigated. The results show that they displayed neuritogenic activity. Based on the observed results, a structure-activity relationship has been established.

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Genes referenced: LOC115919910