ECB-ART-43400
Biol Bull
2014 Apr 01;2262:146-51. doi: 10.1086/BBLv226n2p146.
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Melatonin production in the sea star Echinaster brasiliensis (Echinodermata).
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The primary hormone of the vertebrate pineal gland, melatonin, has been identified broadly throughout the tree of life, in animals, plants, and fungi, supporting a deep evolutionary origin for this signaling molecule. However, some key groups have not been studied. Echinoderms, deuterostome animals, are one of these groups. Herein we study the presence of melatonin and enzymes of its pathway in the sea star Echinaster brasiliensis. We demonstrate that E. brasiliensis produces endogenous melatonin, in the gonads, under a circadian pattern with a nocturnal peak of production. We also show that the enzymes arylalkylamine N-acetyltransferase (AANAT) and tryptophan hydroxylase (TPH) are present and are probably regulating the melatonin production.
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Genes referenced: LOC100887844 LOC115917902 LOC578903