ECB-ART-47592
Ross Fiziol Zh Im I M Sechenova
2001 Nov 01;8711:1557-64.
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[Serotoninergic processes in cells of early embryos of the sea urchin Paracentrotus lividus].
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Agonists of serotonin receptors generate specific inward currents in the cells of early embryos of sea urchin Paracentrotus lividus. Dose-dependent current generated by 5-HT3-agonist 5-HTQ shows complex volt-amperic characteristics with reversal potential -25 and +15 mV. The 5-HTQ effect seems to be due to the activity of channels of mixed conductivity. The 5-HTQ effect is more obvious during cleavage furrow formation. The findings suggest presence of serotonin receptors in the surface membrane of blastomers and their activity play a certain role in regulation of cellular events during cleavage division in the early sea urchin embryo.
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Genes referenced: LOC100887844 LOC100888622