ECB-ART-39009
J Nat Prod
2004 Apr 01;674:584-91. doi: 10.1021/np030427u.
Show Gene links
Show Anatomy links
Cytotoxic sterols and saponins from the starfish Certonardoa semiregularis.
???displayArticle.abstract???
Eleven new polyhydroxysterols (1-11) and eight new saponins (12-19) were isolated from the brine shrimp active fraction of the starfish Certonardoa semiregularis. The structures were determined on the basis of spectral analysis and chemical derivatization. The structural variations of these compounds are due to the hydroxylation pattern of the sterol nucleus, the functionalization of the side chain, or the nature and location of the saccharide moiety. These compounds displayed considerable cytotoxicity against a small panel of human solid tumor cell lines.
???displayArticle.pubmedLink??? 15104487
???displayArticle.link??? J Nat Prod
Genes referenced: LOC100893907 LOC115919910