ECB-ART-36450
Biol Signals
1996 Jan 01;52:101-10. doi: 10.1159/000109179.
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Cyclic ADP-ribose and calcium signaling in eggs.
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Cyclic ADP-ribose is a cyclic nucleotide with Ca2+ signaling functions. It was first discovered in sea urchin eggs and has since been shown to be active in a variety of cells. Another Ca2+ release mechanism recently described in the eggs is mediated by nicotinic acid dinucleotide phosphate, a derivative of NADP+. This article summarizes current results on these two novel Ca(2+)-mobilizing pathways that are independent of inositol trisphosphate.
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Genes referenced: LOC100887844 LOC576539