ECB-ART-32646
Biochem Biophys Res Commun
1986 Jul 16;1381:349-55. doi: 10.1016/0006-291x(86)90287-1.
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Quantitation of a src-like tyrosine protein kinase during fertilization of the sea urchin egg.
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Fertilization of the sea urchin egg is known to involve an increase in overall protein tyrosine kinase activity which precede the first cell division. In order to determine the types of tyrosine kinases that are involved in fertilization, we have used immunological and other criteria to identify a c-src related protein kinase in eggs of the sea urchin L. variegatus. Using an immune complex assay, we have measured the level of this c-src related protein kinase during fertilization and early embryonic development. Fertilization results in a decrease in the c-src kinase detectable by this technique suggesting that c-src does not contribute to the fertilization induced increase in protein tyrosine kinase activity.
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???displayArticle.link??? Biochem Biophys Res Commun
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Genes referenced: LOC100887844 LOC115919910 LOC574936 LOC586799