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Echinobase

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ECB-ANTIBODY-26395543

Antibody Name: phospho-mapk1 Ab4

Common Name: phosphorylated mitogen-activated protein kinase 1

RRID:
Synonyms: E10, active MAP kinase, dual phosphorylated ERK-1/2

Antigens
Gene: mapk1

Clone Type: Monoclonal
Source: New England Biolabs

Antibody
Clone Number E10
Purification Affinity Purification
Isotype IgG1
Host Organism mouse
Echinoderm Reactivity S. purpuratus, P. lividus, L. pictus
Non-Echinoderm Reactivity cow, human, monkey, mouse, pig, rat, zebrafish
Description: Specifically recognizes active form of kinase. Supplied by New England Biolabs (Beverly Hill, MA, USA) and Cell Signaling Technology (#9106).
Immunogen
Name
Type synthetic sequence
Post Translational Modifications Phosphorylated
Source Organism human
Description Sequence corresponding to residues surrounding dual phosphorylation site of human p44 MAP kinase. Also phosphorylated at Tyr (Tyrosine) 204.
Sequence
Reported Usage
western blot
Publications
???displayAntibody.papersFirst??? Caulerpenyne blocks MBP kinase activation controlling mitosis in sea urchin eggs., Eur J Cell Biol 1999  
???displayAntibody.papersRecent??? Autophagy is used as a survival program in unfertilized sea urchin eggs that are destined to die by apoptosis after inactivation of MAPK1/3 (ERK2/1)., Autophagy 2013  
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