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Antibody Name: LOC590586 Ab2 Common Name: tubulin alpha-1A chain RRID: AB_2210201 Synonyms: tyrosinated alpha-tubulin, tyrosylated tubulin, Tyr-Tubulin, YL1/2 Antigens Gene: LOC590586 Clone Type: Monoclonal Source: Thermo Fisher, Sigma-Aldrich

Antibody
Clone Number	YL1/2
Purification	Affinity Purification
Isotype	IgG2a
Host Organism	rat
Echinoderm Reactivity	S. purpuratus,
Non-Echinoderm Reactivity	dog, fruitfly, Hemicentrotus pulcherrimus, human, mouse, pig, rabbit, rat, yeast
Description:	Reacts with a highly conserved ~55 kDa microtubule protein in several echinoid and asteroid species. Has several commercial suppliers, including Thermofisher Scientific (#MA1-80017), Sigma-Aldrich (Chemicon, #MAP1864), and BioRad (Serotec Ltd. (Oxford, UK) (#MCA77G)). Originally created in the lab of J. K. Kilmartin (PMID: 6811596).
Immunogen
Name	Yeast tubulin
Type	polypeptide
Post Translational Modifications	None
Source Organism	Other
Description	Cycle-purified linear protein sequence requiring an aromatic residue at the C-terminus, with two adjacent amino acids being negatively charged (Glu-Glu-Tyr).
Sequence
Reported Usage
immunofluorescence
immunohistochemistry
western blot
Publications
???displayAntibody.papersFirst???	Intermediate filaments, microtubules and microfilaments in epidermis of sea urchin tube foot., Cell Tissue Res 1984
???displayAntibody.papersRecent???	Building the cytokinetic contractile ring in an early embryo: Initiation as clusters of myosin II, anillin and septin, and visualization of a septin filament network., PLoS One 2021
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