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ECB-ANTIBODY-26396263
Antibody Name:
p160 Ab2
Common Name: cell surface protein p160 RRID: Synonyms: p160
Source: |
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Antibody | |
Clone Number | |
Purification | Affinity Purification |
Isotype | IgG |
Host Organism | rabbit |
Echinoderm Reactivity | S. purpuratus |
Non-Echinoderm Reactivity | |
Description: | Function-blocking antibody that reacts with an ~85-kDa fragment, 60-kDa doublet, and 30-kDa doublet corresponding to an integral plasma membrane protein that has been demonstrated to prevent detachment and proper formation of the fertilization envelope. Generated by Sigma-Genosys, The Woodlands, TX for usage by the Wessel lab (Brown University, Providence, RI). |
Immunogen | |
Name | pan p160 |
Type | polypeptide |
Post Translational Modifications | None |
Source Organism | purple sea urchin |
Description | Three bacterially expressed recombinant protein fragments encompassing the majority of the protein (amino acid residues 188-1447) that were each fused to N-terminal Histidine tags. Consists of Segment A (1st CUB motif), Segment B (2nd and 3rd CUB motifs), and Segment C (4th and 5th CUB motifs and transmembrane domain). |
Sequence | |
Reported Usage | |
immunofluorescence | |
immunoprecipitation | |
western blot | |
Publications | |
???displayAntibody.papersFirst??? |
Proteolytic cleavage of the cell surface protein p160 is required for detachment of the fertilization envelope in the sea urchin., Dev Biol 2004 |
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